| General Product Application Suitability | Membrane Filtration | ||||||||||
| Sterilising grade | Mycoplasma retentive | Bioburden reduction | Growth media | Buffers | Product stream | Difficult to filter solutions | Solvents of agressive chemicals | Aqueous solutions | Water filtration | Sterile air/gas | |
| PROPOR SG | |||||||||||
| PROPOR HC | |||||||||||
| PROPOR BR | |||||||||||
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Polyethersulfone (PES) membrane
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0.2µm rated, sterilising grade
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Also available in 0.1µm and 0.45µm
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High flow rates = smaller filter required / quicker processing time
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High throughputs = larger batches
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Low product binding = higher product yield
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Broad-spectrum chemical compatibility
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Low extractables = low leachables into drug product
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Example applications: buffer filtration, final fill
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Polyethersulfone (PES) membrane
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0.2µm rated, sterilising grade
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Integral PES highly asymmetric pre-filter layer
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High capacity, high dirt holding = high throughput with difficult to filter products
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Broad-spectrum chemical compatibility
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Example application: Growth media filtration
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Polyethersulfone (PES) membrane
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0.2µm nominally rated, non-sterilising
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Integral polyester pre-filter layer
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Bioburden reduction
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>5log reduction ASTM F838
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High flow rates = smaller filter required / quicker processing time
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Low product binding = higher product yield
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Broad-spectrum chemical compatibility
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Example application: Chromatography or TFF pre-filtration
